Transplant First

Transplant First

Transplant First aims to increase the number of pre-emptive transplants (transplants before someone needs to start renal replacement therapy) in the UK.

The KQuIP team are supporting regions to restart their work on Quality Improvement (QI) following the suspension of services due to COVID-19.

Read the latest Transplant First newsletter here,

Transplant First started as a project in the West Midlands where we recognised that we had very low rates of pre-emptive transplant listing. The project led to improved rates of pre-emptive listing but also a change in culture around the regional renal teams in promoting QI.

There are currently five regions implementing the project, which has a number of elements:

  1. Regions working with KQUIP receive leadership/QI training and project management support
  2. The delivery team developed a data collection tool which encourages units to perform a mini route cause analysis (RCA) on every patient who reaches dialysis who is potentially suitable for the transplant list but hasn’t yet been listed. If you would like to have access to this tool, email
  3. We have developed a “How to Guide” for people embarking on a similar project
  4. We use opportunities such as UK Kidney Week to share learning and challenge thinking
  5. We communicate learning and resources through this website
  6. We endeavour to work in partnership with other national bodies (e.g. Living Kidney Donor Transplant network, NHS Blood and Transplant)

It is well recognised that for patients with advanced kidney disease, a transplant is the best form of renal replacement therapy. Patients themselves often want to have a transplant as soon as possible to avoid dialysis. Not every patient will be suitable, but if they are, receiving a transplant either before starting dialysis (pre-emptive) or shortly after has been shown to be beneficial.

For patients who have access to living kidney donor transplant (LKDT) there is even more benefit. Despite this, there is huge variability in access to the transplant list. The UK Renal Registry and NHSBT reports show that across the UK, different Renal and transplant units have widely differing rates of pre-emptive transplant listing, time taken to listing, and access to LKDT. For a treatment which is so beneficial to patients and cost-saving, this cannot be acceptable.

When my kidneys failed

Importantly Transplant First is not about:

  • Transplanting people earlier than is good for them
  • Changing listing criteria
  • Favouring the care of pre-emptive patients over those on dialysis

Whether you choose to do Transplant First as a region or do a small QI project in your own unit, thank you for working to improve access to the best care possible on behalf of patients and their donors.

Useful links:

Blood and Transplant Service Guidelines and Standards

The Renal Association Guidelines and Commentaries

NICE Renal replacement therapy and conservative management Guidance

NICE Renal replacement therapy services for adults Quality Standards

Access to transplantation and transplant outcome measures (ATTOM)

NHS Change model and Transplant First


The history of Transplant First 

Transplant First is also on Twitter – follow us @Transplant1stUK


NICE accredited clinical practice guidelines 

Available here

23rd Annual Report

Analyses about the care provided to patients at UK renal centres.

Read the report


A report on the nationwide collection of AKI warning test scores. 

Read the report